Talking Sleep | Sleep Disorders in Military Veterans

Talking Sleep | Sleep Disorders in Military Veterans


Season 7 | Episode 15

In this episode of Talking Sleep, host Dr. Seema Khosla welcomes Dr. Greg Burek, a psychiatrist and former Marine, and Dr. Dmitriy Kogan, associate professor of medicine at the Medical College of Wisconsin and program director for the sleep medicine fellowship program, to discuss the unique sleep challenges facing military veterans and first responders.

The conversation explores how military and first responder training fundamentally changes individuals, creating an “adrenaline-focused” mindset that profoundly impacts their relationship with sleep and health. Dr. Burek provides insider insights into the stages of military service and the concept of “sacrifice” as a unifying characteristic among veterans, while explaining why many veterans may minimize or dismiss their service experiences.

The guests introduce the BRAVE program, an innovative initiative designed specifically for military veterans and first responders to address the “invisible wounds of service”—PTSD and TBI—and their complex interactions with sleep disorders. Unlike traditional VA programs, BRAVE takes a specialized approach to understanding how military culture and experiences create unique sleep medicine challenges.

The discussion covers critical clinical topics including insomnia management in veterans, the frequent use of clonidine as a treatment option, REM behavior disorder presentations that may differ from civilian populations, and the intricate relationships between PTSD, TBI, sleep-disordered breathing, and nightmare disorders. The experts address whether these sleep disturbances stem from combat trauma, brain injury, or the military experience itself.

This episode provides essential insights for healthcare providers treating veterans, including practical approaches to asking about TBI history, understanding military culture’s impact on patient care, and recognizing when specialized referrals may be beneficial.

Whether you’re a sleep medicine practitioner, mental health professional, or healthcare provider serving veteran populations, this episode offers valuable perspectives on culturally competent care for those who have served.
Join us for this enlightening discussion that bridges military culture and sleep medicine to improve care for our veterans and first responders.

Resources

Norepinephrine’s Role in PTSD

  1. Southwick SM, Bremner JD, Rasmusson A, Morgan CA 3rd, Arnsten A, Charney DS. Role of norepinephrine in the pathophysiology and treatment of posttraumatic stress disorder. Biol Psychiatry. 1999;46(9):1192-1204. doi:10.1016/s0006-3223(99)00219-x.
  2. Southwick SM, Krystal JH, Morgan CA, Johnson D, Nagy LM, Nicolaou A, Heninger GR, Charney DS. Abnormal noradrenergic function in posttraumatic stress disorder. Arch Gen Psychiatry. 1993;50(4):266-274.
  3. Raskind MA, Peterson K, Williams T, et al. A Trial of Prazosin for Combat Trauma PTSD With Nightmares in Active-Duty Soldiers Returned From Iraq and Afghanistan. Am J Psychiatry. 2013;170(9):1003-1010. doi:10.1176/appi.ajp.2013.12081133.
  4. Geracioti TD, Baker DG, Kasckow JW, et al. Effects of trauma-related audiovisual stimulation on cerebrospinal fluid norepinephrine and corticotropin-releasing hormone concentrations in post-traumatic stress disorder. Psychoneuroendocrinology. 2008;33(4):416-424. doi:10.1016/j.psyneuen.2008.01.002.
  5. Wimalawansa SJ. Mechanisms of developing post-traumatic stress disorder: new targets for drug development and other potential interventions. CNS Neurol Disord Drug Targets. 2014;13(5):807-816. doi:10.2174/1871527313666140711091026.
  6. Pan X, Kaminga AC, Wen SW, Liu A. Catecholamines in Post-traumatic Stress Disorder: A Systematic Review and Meta-Analysis. Front Mol Neurosci. 2018;11:450. doi:10.3389/fnmol.2018.00450.
  7. Geracioti TD, Baker DG, Ekhator NN, et al. CSF Norepinephrine Concentrations in Posttraumatic Stress Disorder. Am J Psychiatry. 2001;158(8):1227-1230. doi:10.1176/appi.ajp.158.8.1227.
  8. Hendrickson RC, Raskind MA. Noradrenergic dysregulation in the pathophysiology of PTSD. Exp Neurol. 2016;284(Pt B):181-195. doi:10.1016/j.expneurol.2016.05.014.

Clonidine for PTSD

  1. Burek GA, Waite MR, Heslin K, Liewen AK, Yaqub TM, Larsen SE. Low-dose clonidine in veterans with Posttraumatic stress disorder. J Psychiatr Res. 2021;137:480-485. doi:10.1016/j.jpsychres.2021.03.008.
  2. Marchi M, Grenzi P, Boks MP. Clonidine for post-traumatic stress disorder: a systematic review of the current evidence. Eur J Psychotraumatol. 2024;15(1):2366049. doi:10.1080/20008066.2024.2366049.
  3. Bajor LA, Balsara C, Osser DN. An evidence-based approach to psychopharmacology for posttraumatic stress disorder (PTSD) – 2022 update. Psychiatry Res. 2022;317:114840. doi:10.1016/j.psychres.2022.114840.
  4. Boehnlein JK, Kinzie JD. Pharmacologic Reduction of CNS Noradrenergic Activity in PTSD: The Case for Clonidine and Prazosin. J Psychiatr Pract. 2007;13(2):72-78. doi:10.1097/01.pra.0000265763.79753.c1.

Sleep Disorders in PTSD

  1. Mysliwiec V, Gill J, Lee H, et al. Sleep disorders in US military personnel: a high rate of comorbid insomnia and obstructive sleep apnea. Chest. 2013;144(2):549-557. doi:10.1378/chest.13-0088.
  2. Maher MJ, Rego SA, Asnis GM. Sleep disturbances in patients with post-traumatic stress disorder: epidemiology, impact and approaches to management. CNS Drugs. 2006;20(7):567-590. doi:10.2165/00023210-200620070-00003.
  3. El-Solh AA, Riaz U, Roberts J. Sleep Disorders in Patients With Posttraumatic Stress Disorder. Chest. 2018;154(2):427-439. doi:10.1016/j.chest.2018.04.007.
  4. Mysliwiec V, Matsangas P, Gill J, et al. A Comparative Analysis of Sleep Disordered Breathing in Active Duty Service Members with and without Combat-Related Posttraumatic Stress Disorder. J Clin Sleep Med. 2015;11(12):1393-1401. doi:10.5664/jcsm.5272.
  5. Krakow BJ, Ulibarri VA, Moore BA, McIver ND. Posttraumatic stress disorder and sleep-disordered breathing: a review of comorbidity research. Sleep Med Rev. 2015;24:37-45. doi:10.1016/j.smrv.2014.11.001.
  6. Jaoude P, Vermont LN, Porhomayon J, El-Solh AA. Sleep-disordered breathing in patients with post-traumatic stress disorder. Ann Am Thorac Soc. 2015;12(2):259-268. doi:10.1513/AnnalsATS.201407-299FR.
  7. Miller KE, Brownlow JA, Woodward S, Gehrman PR. Sleep and Dreaming in Posttraumatic Stress Disorder. Curr Psychiatry Rep. 2017;19(10):71. doi:10.1007/s11920-017-0827-1.



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